Published January 7, 2008
by Informa Healthcare .
Written in English
|Contributions||Moji C. Adeyeye (Editor), Harry G. Brittain (Editor)|
|The Physical Object|
|Number of Pages||616|
Preformulation solid dosage form development | Moji C Adeyeye; H G Brittain | download | B–OK. Download books for free. Find books. Request PDF | Role of Preformulation in Development of Solid Dosage Forms | Preformulation testing has a significant role in a drug discovery and development program, as it provides valuable. DOI link for Preformulation in Solid Dosage Form Development. Preformulation in Solid Dosage Form Development book. Edited By Moji Christianah Adeyeye, Harry G. Brittain. Edition 1st Edition. First Published eBook Published 7 January Pub. location Boca Raton. Cited by: For any solid dosage forms, preformulation studies become essential to predict the possible process-induced transformations of drugs during a typical manufacturing process. For example, during tableting, the poor flow characteristics exhibited by the powder blend may be improved by adding suitable glidants.
Preformulation testing of solid dosage forms 1. testing is the first step in theis the first step in the rational development of dosage forms of arational development of dosage forms of a drug substance. It can be defined as an investigation of physicalIt can be defined as an investigation of physical and chemical properties. Preformulation in Solid Dosage Form Development 作者: Adeyeye, Moji C. 出版社: Marcel Dekker Inc 出版年: 页数: 定价: $ 装帧: HRD ISBN: Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. a dosage form. Physical Description It is important to understand the physical descrip-tion of a drug substance prior to dosage form development. Most drug substances in use today are solid materials, pure chemical compounds of either crystalline or amorphous constitution. The purity of the chemical substance is essential for its.
Among the various drug delivery routes, the oral route has long been the most popular and convenient route. In this chapter, we focus on the development of oral solid dosage forms including preformulation, drug product development, and manufacturing. Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, Third Edition, edited by James McGinity and Linda A. Felton Dermal Absorption and Toxicity Assessment, Second Edition, edited by Michael S. Roberts and Kenneth A. Walters Preformulation Solid Dosage Form Development, edited by Moji C. Adeyeye and Harry G. Brittain "Preformulation In Solid Dosage Form Development covers every topic of critical importance to the preformulation stages of drug development. Serving as a handbook or stand alone reference, this text will equip those in academia and the pharmaceutical industry with both basic and applied principles for the characterization of drugs, excipients, and products, and will also deal with the issues. Preformulation testing is considered as the first step before rational development of a dosage form with a drug molecule. It involves the exploitation of biopharmaceutical principles in selecting.